Sneaker brand On's promotional products showcasing athletic footwear - Global Banking & Finance Review
Image of On Holding's athletic footwear promotions, highlighting their new Cloudsurfer Max and Cloudboom Max models. This visual reflects On's strategy to enhance sales and capture market share in the competitive sneaker industry.
Finance

Zealand Pharma posts smaller-than-expected Q1 loss as obesity drugs advance

Published by Global Banking & Finance Review

Posted on May 7, 2026

2 min read

· Last updated: May 7, 2026

Add as preferred source on Google

Zealand unveils buyback, Roche payments; shares rise

Zealand Pharma's Strategic Financial Moves and Market Impact

By Jesus Calero and Vera Dvorakova

May 7 (Reuters) - Danish drug developer Zealand Pharma on Thursday unveiled share buyback plans and flagged expected milestone payments from Roche, easing investor concern about how it will fund late-stage obesity trials.

Share Buyback and Roche Milestone Payments

Shares in Zealand rose as much as 18% after the company announced a $200 million buyback and said it expected to book $700 million in milestone payments from Roche this year.

Shift in Investor Sentiment

The move marks a shift in sentiment from March, when Zealand shareholders were disappointed by mid-stage trial results for its petrelintide obesity drug designed to compete with Novo Nordisk's Wegovy and Eli Lilly's Zepbound.

Petrelintide's Unique Mechanism

Petrelintide is a once-weekly obesity drug that works through a different hormone pathway from Wegovy and Zepbound, which Zealand hopes could mean fewer side effects. Wennicke said it could appeal both to GLP-1 dropouts and first-time obesity drug users.

Financial Stability and R&D Commitment

No Compromise on R&D Spend

NO COMPROMISE ON R&D SPEND

Zealand could afford the buyback after recent drug trial progress and incoming Roche payments, without cutting back on research spending, Chief Financial Officer Henriette Wennicke told Reuters.

Future Investment Plans

Wennicke told Reuters that the company planned to invest about $800 million in research over the next five years.

"We will not compromise on our R&D investments," she said.

The company kept its 2026 operating expense guidance unchanged at DKK 2.7 billion to DKK 3.3 billion.

Zealand reported an operating loss of DKK 539 million for the quarter and said its cash position stood at DKK 14.5 billion at the end of March

Market and Analyst Reactions

The buyback, milestone payments and spending plans drew attention away from Zealand's quarterly earnings and back to the strength of its funding base.

Confidence in Pipeline and Future Prospects

Analysts said the buyback demonstrated confidence in Zealand's pipeline. Investors are also watching survodutide, its obesity drug partnered with Boeringer Ingelheim, after late stage data showed weight loss of up to 16.6%.

($1 = 6.3581 Danish crowns)

(Reporting by Jesus Calero and Vera Dvorakova; Editing by Matt Scuffham)

Key Takeaways

  • Q1 loss came in at DKK 539 million vs analysts’ forecast of DKK 672.4 million, driven by momentum in obesity drug development and received positively by markets (marketscreener.com).
  • Cash position declined modestly to DKK 14.47 billion at end-March from DKK 15.11 billion at end-2025; yet the firm launched a USD 200 million share buyback, signaling confidence (marketscreener.com).
  • Zealand expects to receive up to USD 700 million in Roche milestone payments in 2026—including USD 575 million tied to Phase 3 initiation of petrelintide—while advancing to Phase 3 in H2 2026 following positive Phase 2 results (marketscreener.com)

References

Frequently Asked Questions

What was Zealand Pharma's Q1 2024 operating loss?
Zealand Pharma reported a Q1 operating loss of 539 million Danish crowns, which was smaller than analysts expected.
Why did Zealand Pharma's loss beat expectations?
The smaller loss was driven by strong momentum in their obesity drug pipeline and positive developments in obesity drugs.
What share buyback did Zealand Pharma announce?
Zealand Pharma announced a share buyback program worth up to $200 million.
What milestones are expected from Zealand Pharma's Roche partnership?
Zealand Pharma expects to receive $700 million in milestone payments from Roche in 2026, including $575 million for starting Phase 3 trials of petrelintide.
What is petrelintide and why is it important for Zealand Pharma?
Petrelintide is Zealand Pharma's once-weekly experimental obesity drug designed to compete with treatments like Novo Nordisk's Wegovy.

Tags

Related Articles

More from Finance

Explore more articles in the Finance category