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Zealand Pharma posts smaller-than-expected Q1 loss as obesity drugs advance

Published by Global Banking & Finance Review

Posted on May 7, 2026

2 min read

· Last updated: May 7, 2026

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Zealand Pharma Beats Q1 Loss Estimates, Cites Progress in Obesity Therapies

Q1 2024 Financial Results and Strategic Updates

First-Quarter Performance Overview

May 7 (Reuters) - Danish drug developer Zealand Pharma reported a smaller-than-expected first-quarter operating loss on Thursday, boosted by strong momentum in its obesity drug pipeline, and said it would launch a share buyback worth up to $200 million.

Operating Loss and Analyst Expectations

• Zealand's operating loss came in at 539 million Danish crowns ($85 million) in the quarter, compared with analysts' average forecast for a loss of 672.4 million crowns, according to data compiled by LSEG

Cash Position and Financial Health

• The company's cash position stood at 14.47 billion crowns at the end of March, down from 15.11 billion at end-2025

Strategic Initiatives and Guidance

Share Buyback Program

• The Danish drug developer also announced a share buyback of up to $200 million, citing a stronger outlook after positive obesity-drug developments

2026 Guidance and CEO Commentary

• It kept its 2026 guidance unchanged

• CEO Adam Steensberg said advancements during the quarter helped the company strengthen its long-term guidance, and that the company will keep investing heavily in its pipeline

Obesity Drug Pipeline and Partnerships

Milestone Payments from Roche Partnership

• Zealand expects to receive milestone payments of $700 million from its Roche partnership in 2026, including $575 million linked to the initiation of Phase 3 trials with its obesity drug candidate petrelintide

Petrelintide: Zealand's Obesity Drug Candidate

Competitive Positioning

• Petrelintide is Zealand's experimental once-weekly obesity drug, designed to compete with blockbuster weight-loss treatments such as Novo Nordisk's Wegovy

($1 = 6.3581 Danish crowns)

(Reporting by Jesus Calero and Vera Dvorakova; Editing by Matt Scuffham)

Key Takeaways

  • Q1 loss came in at DKK 539 million vs analysts’ forecast of DKK 672.4 million, driven by momentum in obesity drug development and received positively by markets (marketscreener.com).
  • Cash position declined modestly to DKK 14.47 billion at end-March from DKK 15.11 billion at end-2025; yet the firm launched a USD 200 million share buyback, signaling confidence (marketscreener.com).
  • Zealand expects to receive up to USD 700 million in Roche milestone payments in 2026—including USD 575 million tied to Phase 3 initiation of petrelintide—while advancing to Phase 3 in H2 2026 following positive Phase 2 results (marketscreener.com)

References

Frequently Asked Questions

What was Zealand Pharma's Q1 2024 operating loss?
Zealand Pharma reported a Q1 operating loss of 539 million Danish crowns, which was smaller than analysts expected.
Why did Zealand Pharma's loss beat expectations?
The smaller loss was driven by strong momentum in their obesity drug pipeline and positive developments in obesity drugs.
What share buyback did Zealand Pharma announce?
Zealand Pharma announced a share buyback program worth up to $200 million.
What milestones are expected from Zealand Pharma's Roche partnership?
Zealand Pharma expects to receive $700 million in milestone payments from Roche in 2026, including $575 million for starting Phase 3 trials of petrelintide.
What is petrelintide and why is it important for Zealand Pharma?
Petrelintide is Zealand Pharma's once-weekly experimental obesity drug designed to compete with treatments like Novo Nordisk's Wegovy.

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