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S

Spyre Therapeutics SYRE · USD

Health Care · US listing · 🇺🇸 United States

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109.00

+4.95%

Close of 9 Nov 2026, in USD

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Reference data, closing prices and charts across 45,000 companies, plus crypto, commodities and currencies.

Largest shareholders

As filed, so dates differ, and a group and its funds can both appear.

HolderSharesStakeChangeFiled
FMR LLC11.8m18.39%+142.2k31 Mar 2026
Fidelity Management & Research Company LLC11.5m18.00%+2.6m31 Dec 2025
BLACKROCK, INC.5.5m8.62%−88031 Mar 2026
BlackRock Institutional Trust Company, N.A.5m7.80%+1.4m31 Dec 2025
RTW INVESTMENTS, LP4.2m6.51%—31 Mar 2026
RTW Investments L.P.4.2m6.51%+550k31 Dec 2025
The Vanguard Group, Inc.4m6.28%+979.7k31 Dec 2025
Fairmount Funds Management LLC4m6.27%—31 Dec 2025
FAIRMOUNT FUNDS MANAGEMENT LLC4m6.27%—31 Mar 2026
PERCEPTIVE ADVISORS LLC3.8m5.91%+714k31 Mar 2026
VR Adviser, LLC3.7m5.75%+1m31 Dec 2025
VR ADVISER, LLC3.7m5.75%—31 Mar 2026
Capital International Investors3.5m5.45%+1.1m31 Dec 2025
Perceptive Advisors LLC3.1m4.79%+1.8m31 Dec 2025
VANGUARD CAPITAL MANAGEMENT LLC3.1m4.77%+3.1m31 Mar 2026

Short interest

Shares sold short, 15 Oct 2026. US exchange data.

12.5m

-2.6% on the period before. 7.3 days to cover.

Short volume

Share of the day's trading sold short, 4 Nov 2026

66.2%

Last 60 trading days.

Failed deliveries

Shares not delivered on settlement, from the SEC

  • 24 Sept 2026788 shares
  • 21 Sept 20265,660 shares
  • 18 Sept 202627 shares
  • 14 Sept 20269 shares
  • 10 Sept 202624,790 shares

Sources and methodology

Data on this tab
Our data supplier
Chart on the Overview
TradingView

Nothing here is investment advice. Prices can be delayed or wrong, so check with the exchange before relying on them. Data for this page. How we cover markets.