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Transcode Therapeutics RNAZ · USD

Health Care · US listing · 🇺🇸 United States

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1.54

+3.36%

Close of 9 Nov 2026, in USD

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About Transcode Therapeutics

From its filings with the US Securities and Exchange Commission

SEC filings

Transcode Therapeutics is based in Boston, Massachusetts and is incorporated in Delaware. Its shares trade on Nasdaq under the ticker RNAZ. The SEC classifies its business as pharmaceutical preparations. In the fiscal year to 31 December 2025, it reported a net loss of $34.7m. At that date it held total assets of $162.4m and shareholders' equity of $10.3m.

In its own words

Polynoma Acquisition. On October 8, 2025, we entered into a Membership Interest Purchase Agreement (the “Purchase Agreement”) with DEFJ, LLC, a Delaware limited liability company, (“DEFJ”) pursuant to which we acquired 100% of the issued and outstanding membership interests of ABCJ, LLC, a Delaware limited liability company, (“ABCJ”) (such transaction, the “Acquisition”). In the Acquisition, we issued 1,152.9568 shares of our Series A Non-Voting Convertible Preferred Stock (the “Series A Preferred Stock”) to DEFJ. Each share of Series A Preferred Stock is convertible into 10,000 shares of common stock. Prior to the Acquisition, ABCJ was a wholly owned subsidiary of DEFJ and an indirect wholly owned subsidiary of CK Life Sciences Int’l., (Holdings) Inc., a listed entity on the Main Board of the Hong Kong Stock Exchange.

ABCJ owns 100% of the issued and outstanding membership interests of Polynoma, LLC, a Delaware limited liability company, (“Polynoma”) headquartered in San Diego, California. Polynoma is an immuno-oncology focused biopharmaceutical company developing Seviprotimut-L, an investigational polyvalent antigen vaccine intended to reduce the risk of recurrence of cancer in patients with stage IIB and IIC melanoma who have limited options. Seviprotimut-L has been safely administered in clinical trials to more than 1,000 patients.

Quoted from its 10-K, filed 15 Apr 2026. Read the filing on SEC.gov ↗

Company facts

Sector
Health Care
Industry
Biotechnology
Listed since
28 Apr 2021
Employees
19
Head office
6 LIBERTY SQUARE, BOSTON, MA, 02109
Incorporated in
DE
Classification
Pharmaceutical Preparations
Filer status
<br>Emerging growth company

Leadership

Pay as last reported

  • Dr. Philippe CalaisExecutive Chairman of the Board, Chief Executive Officer, since 2021$112,611
  • Mr. Thomas FitzgeraldChief Financial Officer, Vice President, Director, since 2018$956,966
  • Dr. Daniel VlockChief Medical Officer
  • Ms. Elizabeth CzerepakIndependent Director
  • Dr. Erik MantingIndependent Director$73,111
  • Dr. Magda MarquetIndependent Director$75,111
  • Mr. Jack StoverIndependent Director

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
0
Environment
0
Social
0
Governance
0

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Transcode Therapeutics focuses on innovative cancer diagnostics and therapeutics like TTX-MC138 targeting microRNA-10b.
  • The company has multiple preclinical programs including TTX-siPDL1 and TTX-siLIN28B for solid tumors.
  • Transcode Therapeutics' lead candidate TTX-MC138 addresses multiple cancer types including breast and pancreatic cancer.

Weaknesses

  • Transcode Therapeutics has only 19 full-time employees which may limit operational capacity.
  • The company's IPO on April 28, 2021, indicates limited financial resources for expansion.
  • Transcode Therapeutics operates from Boston, Massachusetts with no mention of international presence.

Opportunities

  • The growing biotechnology sector in the US offers potential for Transcode Therapeutics to expand its research programs.
  • Transcode Therapeutics can leverage its TTX-RIGA program to target innate immunity in tumor microenvironments.
  • The company's TTX-mRNA platform presents opportunities for developing cancer vaccines in the Health Care sector.

Threats

  • The biotechnology industry faces intense competition from established pharmaceutical companies.
  • Regulatory challenges in the Health Care sector could delay the commercialization of TTX-MC138.
  • The company's reliance on preclinical programs without approved products poses significant market entry risks.

Sources and methodology

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