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Ultragenyx Pharmaceutical RARE · USD

Health Care · US listing · 🇺🇸 United States

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16.41

+6.35%

Close of 9 Nov 2026, in USD

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About Ultragenyx Pharmaceutical

From its filings with the US Securities and Exchange Commission

SEC filings

Ultragenyx Pharmaceutical is based in Novato, California and is incorporated in Delaware. Its shares trade on Nasdaq under the ticker RARE. The SEC classifies its business as pharmaceutical preparations. In the fiscal year to 31 December 2025, it reported revenue of $673.0m and a net loss of $575.0m. At that date it held total assets of $1.53bn and shareholders' equity of −$80.0m. By region, North America accounted for 56.0%, followed by Latin America [Member] at 25.3% and EMEA [Member] at 16.0%.

In its own words

We are a biopharmaceutical company committed to bringing novel products to patients for the treatment of serious rare and ultra-rare genetic diseases. We have built a diverse portfolio of approved therapies and product candidates aimed at addressing diseases with high unmet medical need and clear biology for treatment, for which there are typically no approved therapies treating the underlying disease.

We were founded in April 2010 by our President and Chief Executive Officer, Emil Kakkis, M.D., Ph.D., and are led by a management team experienced in the development and commercialization of rare disease therapeutics. Our strategy is predicated upon time- and cost-efficient drug development, with the goal of delivering safe and effective therapies to patients with the utmost urgency.

Our current approved therapies and clinical-stage pipeline consist of four product categories: biologics, small molecules, AAV gene therapy, and nucleic acid product candidates.

Crysvita is a fully human monoclonal antibody administered via subcutaneous injection, that targets fibroblast growth factor 23, or FGF23, developed for the treatment of XLH. XLH is a rare, hereditary, progressive, and lifelong musculoskeletal disorder characterized by renal phosphate wasting caused by excess FGF23 production. There are approximately 48,000 patients with XLH in the developed world, including approximately 36,000 adults and 12,000 children. Crysvita is the only approved treatment that addresses the underlying cause of XLH.

Quoted from its 10-K, filed 18 Feb 2026. Read the filing on SEC.gov ↗

Company facts

Sector
Health Care
Industry
Biotechnology
Listed since
31 Jan 2014
Employees
1,371
Head office
60 LEVERONI COURT, NOVATO, CA, 94949
Incorporated in
DE
Classification
Pharmaceutical Preparations
Filer status
Large accelerated filer

Leadership

Pay as last reported

  • Mr. Daniel WelchIndependent Chairman of the Board$500,134
  • Dr. Emil KakkisPresident, Chief Executive Officer, Director, since 2010$13.7m
  • Mr. Howard HornChief Financial Officer, Executive Vice President, Corporate Strategy$4.3m
  • Mr. Dennis HuangExecutive Vice President, Chief Technical Operations Officer, Gene Therapy Operations$4.2m
  • Dr. Eric CrombezExecutive Vice President, Chief Medical Officer$4.3m
  • Mr. Erik HarrisExecutive Vice President, Chief Commercial Officer$4.3m
  • Mr. Eric OlsonChief Business Officer, Executive Vice President
  • Ms. Karah ParschauerExecutive Vice President, Chief Legal Officer, Corporate Affairs$4.0m
  • Mr. John PinionChief Quality Officer, Executive Vice President - Translational Sciences$4.1m
  • Dr. Deborah DunsireIndependent Director$466,759
  • Mr. Matthew FustIndependent Director$480,134
  • Mr. Michael NarachiIndependent Director$481,884

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
68
Environment
44
Social
99
Governance
60
Women in the workforce
55.7%
Carbon reduction policy
Yes
Human rights policy
Yes

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Ultragenyx Pharmaceutical Inc, a leading biopharmaceutical company, possesses several strengths that contribute to its success:

Weaknesses

  • Despite its strengths, Ultragenyx Pharmaceutical Inc also faces certain weaknesses:

Opportunities

  • Ultragenyx Pharmaceutical Inc can leverage the following opportunities to enhance its market position:

Threats

  • Ultragenyx Pharmaceutical Inc should be mindful of the following threats that could impact its business:

Sources and methodology

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