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Lyra Therapeutics LYRA · USD

Health Care · US listing · 🇺🇸 United States

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Close of 5 Nov 2026, in USD

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About Lyra Therapeutics

Its shares trade under the ticker LYRA. It has been listed since 1 May 2020. In the fiscal year to 31 December 2025, it reported revenue of $398,000 and a net loss of $28.9m. At that date it held total assets of $36.1m and shareholders' equity of −$10.7m.

Lyra Therapeutics, Inc. is a clinical-stage therapeutics company. The company is headquartered in Watertown, Massachusetts. The company went IPO on 2020-05-01. The Company’s product candidates, LYR-210 and LYR-220, are bioresorbable polymeric matrices designed to be administered in a non-invasive, in-office procedure and intended to deliver up to six months of continuous drug therapy to the sinonasal passages for the treatment of chronic rhinosinusitis (CRS). LYR-210 is an anti-inflammatory implantable drug matrix based on its XTreo platform that is designed to locally elute mometasone furoate (MF) to the inflamed mucosal tissue for up to six months in surgically-naive CRS patients who fail medical management. The company has developed LYR-220 for use in CRS patients who continue to require treatment to manage CRS symptoms despite having had sinus surgery.

Figures and description from our data supplier, not checked against the company's own report.

Company facts

Sector
Health Care
Industry
Pharmaceuticals
Listed since
1 May 2020
Employees
38
Head office
480 ARSENAL WAY, WATERTOWN, MA, 02472
Incorporated in
DE
Classification
Surgical & Medical Instruments & Apparatus
Filer status
Non-accelerated filer<br>Smaller reporting company

Leadership

Pay as last reported

  • Dr. Richard NiemanChief Medical Officer$1.4m
  • Mr. James TobinLead Independent Director$100,669
  • Ms. C. Ann MerrifieldIndependent Director$61,419
  • Mr. W. Bradford SmithIndependent Director$72,169
  • Dr. Nancy SnydermanIndependent Director$62,732

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
50
Environment
51
Social
71
Governance
27
Carbon reduction policy
No
Human rights policy
No

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Lyra Therapeutics has 38 employees focused on clinical-stage therapeutics in the Health Care sector.
  • LYR-210 and LYR-220 are bioresorbable polymeric matrices for chronic rhinosinusitis treatment.
  • The XTreo platform enables six months of continuous drug therapy in non-invasive procedures.

Weaknesses

  • The company has only 38 employees for a clinical-stage therapeutics company.
  • LYR-210 targets surgically-naive CRS patients who fail medical management.
  • LYR-220 is for CRS patients who continue treatment after sinus surgery.

Opportunities

  • The US market offers opportunities for chronic rhinosinusitis treatments.
  • The XTreo platform could expand to other therapeutic areas.
  • The company's IPO on 1 May 2020 provides capital for growth.

Threats

  • The Health Care sector faces regulatory challenges for new drug approvals.
  • Chronic rhinosinusitis treatments compete with existing medical management options.
  • The company's small size may limit resources for clinical trials.

Sources and methodology

Data on this tab
Our data supplier
Chart on the Overview
TradingView

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