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Black Diamond Therapeutics BDTX · USD

Health Care · US listing · 🇺🇸 United States

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1.86

+6.90%

Close of 9 Nov 2026, in USD

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About Black Diamond Therapeutics

From its filings with the US Securities and Exchange Commission

SEC filings

Black Diamond Therapeutics is based in Cambridge, Massachusetts. Its shares trade on Nasdaq under the ticker BDTX. The SEC classifies its business as biological products, (no diagnostic substances). In the fiscal year to 31 December 2025, it reported revenue of $70.0m and net income of $22.4m. At that date it held total assets of $143.0m and shareholders' equity of $112.2m.

In its own words

We are a clinical-stage oncology company developing MasterKey therapies that target families of oncogenic mutations in patients with cancer. The foundation of our company is built upon a deep understanding of cancer genetics, onco-protein structure and function, and medicinal chemistry. Our MasterKey therapies are designed to address a broad spectrum of genetically defined tumors, overcome resistance, minimize wild-type mediated toxicities, and be brain-penetrant to treat central nervous system (CNS) disease. Our compounds target families of oncogenic mutations in clinically validated pathways. Our lead clinical-stage program, silevertinib (formerly BDTX-1535), a brain-penetrant, fourth-generation epidermal growth factor receptor (EGFR) MasterKey inhibitor, is currently being studied in a Phase 2 clinical trial in patients with epidermal growth factor receptor mutant (EGFRm) non-small cell lung cancer (NSCLC). We plan to initiate a randomized Phase 2 trial of silevertinib in newly diagnosed patients with EGFR altered glioblastoma (GBM) in the second quarter of 2026.

Our MasterKey therapies were discovered using our proprietary MAP drug discovery engine which was built on three central pillars: identification of oncogenic mutations, confirmation of oncogenicity of mutations based upon cell and tumor models, and pharmacologic inhibition of the relevant mutations while sparing wild-type.

Quoted from its 10-K, filed 16 Mar 2026. Read the filing on SEC.gov ↗

Company facts

Sector
Health Care
Industry
Biotechnology
Listed since
30 Jan 2020
Employees
21
Head office
245 FIRST STREET, 18TH FLOOR, CAMBRIDGE, MA, 02142
Classification
Biological Products, (No Diagnostic Substances)
Filer status
Non-accelerated filer<br>Smaller reporting company

Leadership

Pay as last reported

  • Dr. Mark VellecaChairman of the Board, President, Chief Executive Officer, since 2021$2.9m
  • Dr. Elizabeth BuckCo-Founder, Chief Scientific Officer
  • Ms. Erika JonesSenior Vice President - Finance, Principal Financial Officer and Principal Accounting Officer
  • Mr. Brent Hatzis-SchochChief Operating Officer, General Counsel$1.4m
  • Ms. Melanie MorrisonChief Development Officer
  • Dr. Sergey YurasovChief Medical Officer$1.5m
  • Dr. Samarth KulkarniLead Independent Director$171,347
  • Dr. Ali BehbahaniIndependent Director$159,847
  • Ms. Shannon CampbellIndependent Director$352,200
  • Dr. Kapil DhingraIndependent Director$186,747
  • Dr. Garry MenzelIndependent Director$162,347
  • Dr. Prakash RamanIndependent Director$356,896

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
55
Environment
55
Social
90
Governance
21
Women in the workforce
58%
Carbon reduction policy
No
Human rights policy
No

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Black Diamond Therapeutics Inc. utilizes advanced technologies in the field of precision oncology, allowing for the development of innovative therapies.
  • The company has a robust and diversified pipeline of targeted therapeutics, which reduces dependency on a single product or approach.

Weaknesses

  • As a relatively new entrant in the market, Black Diamond Therapeutics Inc. may face challenges in establishing its brand and gaining market share.
  • The company's financial resources and operational capabilities might be limited, which could impact research and development activities.

Opportunities

  • With growing awareness and understanding of precision medicine, the demand for targeted therapies is expected to rise, presenting an opportunity for Black Diamond Therapeutics Inc.
  • Expanding into emerging markets provides the company with access to a larger patient population and potential for increased revenue.

Threats

  • The presence of established pharmaceutical companies in the precision oncology field may pose a threat to Black Diamond Therapeutics Inc.'s market share and growth.
  • Stringent regulatory requirements in the healthcare industry can create barriers to entry for new therapies, which could potentially hinder the company's progress.

Sources and methodology

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