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Arrowhead Pharmaceuticals ARWR · USD

Health Care · US listing · 🇺🇸 United States

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49.24

-15.34%

Close of 9 Nov 2026, in USD

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About Arrowhead Pharmaceuticals

From its filings with the US Securities and Exchange Commission

SEC filings

Arrowhead Pharmaceuticals is based in Pasadena, California and is incorporated in Delaware. Its shares trade on Nasdaq under the ticker ARWR. The SEC classifies its business as pharmaceutical preparations. In the fiscal year to 30 September 2025, it reported revenue of $829.4m and a net loss of $1.6m. At that date it held total assets of $1.39bn and shareholders' equity of $466.1m.

In its own words

The Company develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and modes of delivery, the Company’s therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes.

There are currently 18 Arrowhead discovered drug candidates in clinical trials ranging from early stage (Phase 1) to late stage (Phase 3). In addition, the company has a robust discovery stage pipeline which is capable of generating multiple new clinical candidates each year.

The Company recently achieved a transformational milestone with its first commercial launch in 2025, when the U.S. Food and Drug Administration ("FDA") approved REDEMPLO® (plozasiran) as an adjunct to diet to reduce triglycerides in adults with Familial Chylomicronemia Syndrome ("FCS"). Additionally, phase 3 studies (SHASTA-3, SHASTA-4 and SHASTA-5) for severe hypertriglyceridemia ("sHTG") have been fully enrolled and the Company plans to file a supplemental NDA for this indication in 2026, pending successful completion of Phase 3 clinical studies. The Company has built a commercial organization to support marketing in FCS, a rare disease, and plans to progressively build its commercial capabilities to also support marketing in sHTG, a higher prevalence disease which will require a larger commercial footprint.

Quoted from its 10-K, filed 25 Nov 2025. Read the filing on SEC.gov ↗

Company facts

Sector
Health Care
Industry
Biotechnology
Listed since
14 Dec 1993
Employees
711
Head office
177 E COLORADO BLVD, PASADENA, CA, 91105
Incorporated in
DE
Classification
Pharmaceutical Preparations
Filer status
Large accelerated filer

Leadership

Pay as last reported

  • Dr. Christopher AnzaloneChairman of the Board, President, Chief Executive Officer, since 2007$12.4m
  • Mr. Daniel ApelChief Financial Officer
  • Mr. Patrick O'BrienChief Operating Officer, General Counsel, Company Secretary$3.9m
  • Mr. James HamiltonChief of Discovery and Translational Medicine, since 2023$3.5m
  • Mr. William WaddillLead Independent Director$470,833
  • Dr. Mauro FerrariIndependent Director$460,833
  • Mr. Douglas IngramIndependent Director
  • Dr. Hongbo LuIndependent Director$804,999
  • Dr. Adeoye OlukotunIndependent Director$460,833
  • Dr. Michael PerryIndependent Director$460,833
  • Ms. Victoria VakienerIndependent Director$460,833
  • Mr. Vincent AnzaloneInvestor Relations, since 2018

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
48
Environment
48
Social
72
Governance
22
Women in the workforce
51%
Carbon reduction policy
No
Human rights policy
No

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Arrowhead Pharmaceuticals Inc has several strengths that contribute to its success:

Weaknesses

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Opportunities

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Threats

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Sources and methodology

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