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Agenus AGEN · USD

Health Care · US listing · 🇺🇸 United States

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7.15

0.00%

Close of 9 Nov 2026, in USD

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About Agenus

From its filings with the US Securities and Exchange Commission

SEC filings

Agenus is based in Lexington, Massachusetts and is incorporated in Delaware. Its shares trade on Nasdaq under the ticker AGEN. The SEC classifies its business as biological products, (no diagnostic substances). In the fiscal year to 31 December 2025, it reported revenue of $114.2m and a net loss of $3.1m. At that date it held total assets of $226.8m and shareholders' equity of −$271.1m. By region, United States [Member] accounted for 99.1%, followed by Rest of World [Member] at 0.9%.

In its own words

Agenus is a clinical-stage biotechnology company focused on discovering and developing immunotherapies for cancer and infectious disease. Our primary business is immuno-oncology ("I-O"), where we are advancing antibody-based programs to activate innate and adaptive immunity, overcome tumor immune evasion and expand the population of patients who may benefit from immunotherapy. Our lead clinical program is botensilimab (“BOT” or “AGEN1181”), alone and in combination with balstilimab (“BAL”). We also maintain select clinical-stage immuno-oncology assets, which may be used as standalone agents or be complimentary to botensilimab plus balstilimab (“BOT/BAL”). Agenus also maintains an equity investment in MiNK Therapeutics, Inc. ("MiNK"), with an approximate fair value of $24.3 million as of December 31, 2025, and a majority ownership of a vaccine adjuvant business through our subsidiary SaponiQx, Inc. ("SaponiQx").

Our strategy is to focus capital on execution of programs that we believe have the clearest path to meaningful clinical and commercial value, led by BOT/BAL in colorectal cancer and selected other tumor types. We intend to advance late-stage development and support responsible paid patient access programs as well as clinical trials. We maintain manufacturing flexibility through strategic collaborations with an emphasis on our Zydus collaboration.

Quoted from its 10-K, filed 16 Mar 2026. Read the filing on SEC.gov ↗

Company facts

Sector
Health Care
Industry
Biotechnology
Listed since
4 Feb 2000
Employees
81
Head office
3 FORBES ROAD, LEXINGTON, MA, 02421
Incorporated in
DE
Classification
Biological Products, (No Diagnostic Substances)
Filer status
Accelerated filer<br>Smaller reporting company

Leadership

Pay as last reported

  • Dr. Garo ArmenChairman of the Board, Chief Executive Officer, Co-Founder, since 1994$3.7m
  • Ms. Christine KlaskinVice President - Finance$483,477
  • Mr. Richard GoldbergChief Development Officer
  • Dr. Steven O'DayChief Medical Officer$968,491
  • Mr. Timothy WrightLead Independent Director$232,883
  • Dr. Jennifer BuellDirector, since 2018$7.4m
  • Mr. Brian CorveseIndependent Director$490,308
  • Mr. Thomas HarrisonIndependent Director$64,677
  • Ms. Susan HirschIndependent Director$138,950

Environmental, social and governance

Scores out of 100, from our data supplier

ESG
Overall
36
Environment
15
Social
65
Governance
29
Carbon reduction policy
No
Human rights policy
No

SWOT analysis

AI-generated by our data supplier. Not written or checked by our editors.

AI-generated

Strengths

  • Agenus Inc develops clinical-stage immuno-oncology technologies for cancer treatment in the US Health Care sector.
  • Agenus focuses on antibody discovery platforms like Retrocyte Display and SECANT yeast display in biotechnology.
  • Agenus Inc's vaccine programs include Prophage, AutoSynVax, and PhosPhoSynVax for infectious diseases.

Weaknesses

  • Agenus Inc has 81 employees, which is lower than the industry average for biotechnology companies.
  • Agenus Inc's headquarters in Lexington, Massachusetts, is not a major biotech hub like Boston.
  • Agenus Inc's IPO in 2000 is over 20 years old, indicating limited recent market activity.

Opportunities

  • Agenus Inc can expand its vaccine programs into the global market for infectious diseases.
  • Agenus Inc's antibody discovery platforms can be licensed to other biotech firms for revenue generation.
  • Agenus Inc's checkpoint modulator programs may attract partnerships with larger pharmaceutical companies.

Threats

  • Agenus Inc faces competition from established biotech companies in the US Health Care sector.
  • Agenus Inc's reliance on a single platform, QS-21 Stimulon adjuvant, poses a risk to its vaccine programs.
  • Agenus Inc's clinical-stage development requires significant funding, which may be challenging to secure.

Sources and methodology

Data on this tab
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