NGS Sample Preparation Market to Surpass $8.5 Billion by 2032, Driven by Precision Oncology & Global Research Expansion

According to a recent report released on the industry by award-winning consulting firm Fact.MR, the worldwide NGS sample preparation market is likely to outpace a valuation of US$ 8.5 billion by 2032, widening at a CAGR of 7.3% over the forecast period of 2022-2032. Next generation sequencing (NGS) has revolutionized genomic research, laying the foundation for remarkably effective diagnosis of myriad chronic and infectious diseases, an obvious truth that is boding well for the future.

From 2015 to 2021, demand for NGS sample preparation experienced an incline at a CAGR of 7.5%, concluding at a value of US$ 3.8 Billion. NGS has been widely used in clinical oncology to promote customized cancer treatment in recent years. The method has been shown to be effective in discovering novel and uncommon cancer mutations, locating cancer mutation carriers in families, and giving molecular basis for targeted therapy.

As a result, leading manufacturers are launching a wave of sample preparation solutions, with prospects aplenty across Asia. For example, in May 2021, BGI Group and Ethiopian Biotechnology Institute (EBiT) signed a Memorandum of Understanding to execute an HPV genotyping pilot project and complete 2,000 sample screenings in Ethiopia in order to build a new paradigm of HPV screening, diagnosis, and treatment.

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Key Takeaways from the Market Study:

• Global NGS sample preparation market is likely to double from 2022-2032.By product type, NGS sample preparation kits, reagents & consumables to hold 41% revenue.
• Drug & biomarker discovery to remain dominant application area, accounting for over 2/5th of revenue.
• U.S. to be the most opportunistic market, expected to flourish at a 7.1% CAGR.India to generate significant prospects, flourishing at a CAGR of 6.6% until 2032.

"Notable NGS sample preparation product makers are venturing into unknown territory by foraying into areas such as animal and plant health to produce highly advanced diagnostic procedures and handle different diseases, broadening their expansion potential," says a Fact.MR Analyst.

University-Level Collaborations Fuel Advancements in NGS Sample Preparation Technologies

As next-generation sequencing (NGS) continues to gain traction in clinical diagnostics, certain operational challenges persist—particularly in the areas of library preparation and automation. Traditional pipetting workstations, although effective for high-throughput processing, often lack the necessary flexibility during workflows. This has led to growing interest in microfluidic technologies, which offer distinct advantages such as miniaturization, enhanced precision, and lower investment costs.

To overcome current limitations and accelerate innovation, several organizations are partnering with academic institutions to explore and refine microfluidic systems for use in NGS sample preparation. These collaborative efforts are particularly focused on improving automation in library preparation workflows. Although microfluidic systems are still in the early stages of commercialization, such research partnerships are expected to yield advanced solutions that enhance efficiency, reduce costs, and simplify NGS protocols in the years to come.

NGS Sample Preparation Expands Applications in Agriculture and Plant Pathology

Beyond clinical settings, NGS sample preparation is becoming increasingly valuable in agriculture, particularly in the diagnosis and monitoring of plant and crop diseases. The growing field of agricultural genomics—or agrigenomics—is at the forefront of developing sustainable farming practices and addressing global food security challenges.

One of the key areas of application is in viral genomics, where NGS technologies are utilized to detect and trace the spread of plant-borne viral infections that significantly impact crop yield and quality. Unlike traditional methods, NGS enables an unbiased and hypothesis-free analysis of plant samples, facilitating the early identification of pathogens and allowing for more targeted intervention strategies. As demand for sustainable agriculture intensifies, the integration of NGS sample preparation in plant disease diagnostics is poised to become a cornerstone of modern agritech innovations.

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Competitive Landscape

The worldwide NGS sample preparation market looks to be fragmented, as evidenced by the existence of various regional and global market competitors. Introduction of cutting-edge testing kits, partnership with current manufacturers, and acquisition of other businesses are all major expansion tactics.

1. F. Hoffmann-La Roche's subsidiary Geronimo Acquisition Corp. bought shares in GenMark Diagnostics Inc. in a tender offering in April 2021 to expand its in-class molecular diagnostics range and advance research in antibiotic resistance and infectious illnesses.
2. Agilent Technologies finalized and released a CE-IVD certified qRT-PCR in vitro diagnostic kit for the detection of SARS-CoV-2 RNA in March 2021, which was validated using a number of commercially available RNA extraction kits.

More Insights Available

Fact.MR, in its new offering, presents an unbiased analysis of the global NGS sample preparation market, presenting historical analysis from 2015 to 2021 and forecast statistics for the period of 2022-2032.

The study reveals essential insights on the basis of product type (instruments and kits, reagents & consumables), application (drug & biomarker discovery, diagnostics, precision medicine and others (agriculture and animal research)) and end user (hospitals & diagnostic centers, biotechnology & pharmaceutical companies, academic & research institutes and others (CROs and CMOs)) across six major regions (North America, Latin America, Europe, East Asia, South Asia & Oceania and Middle East & Africa).

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