Finance

GSK beats quarterly profit estimates on strength in respiratory, general medicines

Published by Global Banking & Finance Review

Posted on April 29, 2026

2 min read

· Last updated: April 29, 2026

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GSK beats quarterly profit estimates on strength in respiratory, general medicines

GSK posts quarterly profit, sales beat in boost for new CEO Miels

GSK's Strong First-Quarter Performance and Outlook

By Bhanvi Satija

Quarterly Results and Market Expectations

LONDON, April 29 (Reuters) - British drugmaker GSK reported first-quarter profit and sales above analysts' expectations on Wednesday, helped by strong demand for its respiratory medicines and vaccines, giving a boost for new CEO Luke Miels who took over this year.

The company also backed its full-year forecast of 3% to 5% sales growth and core operating profit growth of 7% to 9%.

Leadership Transition and Strategic Challenges

The quarterly results mark the first full-quarter under Miels who is tasked with navigating the 2028 patent expiration for GSK's key HIV medicine, dolutegravir, by bolstering its pipeline of newer drugs.

CEO Miels' Vision and R&D Focus

Miels, who previously served as the company's Chief Commercial Officer, is under pressure to prove that GSK's research and development engine can deliver on its long-term revenue targets of over 40 billion pounds by 2031.

Analysts expect about 35 billion pounds in sales that year.

"Alongside operational delivery, we are focused on execution and accelerating R&D", Miels said.

Key Financial Highlights

GSK posted first-quarter revenue of 7.63 billion pounds ($10.30 billion), compared with expectations of 7.58 billion pounds.

Sales of its shingles vaccine, Shingrix, came in at 1.03 billion pounds, above expectations of 851 million pounds, marking a record quarter.

GSK said sales were helped by increased demand in Europe and launch of a pre-filled syringe in the United States.

The drugmaker posted core earnings per share of 46.5 pence for the three months ended March 31, compared with analyst expectations of 43.3 pence, according to company-provided consensus estimates.

Additional Information

($1 = 0.7405 pounds)

(Reporting by Bhanvi Satija in London; Editing by Andrew Heavens and Louise Heavens)

Key Takeaways

  • GSK’s Q1 core EPS of 46.5 pence beat the 43.3 pence consensus, boosting investor confidence
  • Growth was fueled by strength in respiratory treatments like Trelegy (up 15 %) and stable general medicines sales
  • While specialty medicines continue to drive momentum, GSK signals that vaccines and general medicines may see low‑single‑digit headwinds in 2026

Frequently Asked Questions

What did GSK report for its first-quarter core earnings per share?
GSK reported core earnings per share of 46.5 pence for the first quarter.
What contributed to GSK's better-than-expected quarterly profits?
Strong sales of respiratory and general medicines helped GSK exceed profit estimates.
How did GSK's profits compare to analyst expectations?
GSK's core earnings per share outpaced the 43.3 pence expected by analysts.
Which segment of GSK's business drove its Q1 performance?
The respiratory and other general medicines segment drove GSK's Q1 performance.

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