Published by Global Banking & Finance Review®
Posted on April 1, 2025
4 min readLast updated: January 24, 2026
Add as preferred source on GoogleThe Trump administration has initiated mass layoffs at US health agencies, affecting 10,000 staffers, as part of a downsizing plan, raising concerns about public health responses.
By Leah Douglas and Marisa Taylor
WASHINGTON (Reuters) -The Trump administration began mass layoffs of 10,000 staffers at U.S. health agencies on Tuesday, according to multiple sources familiar with the situation, with security guards barring entry to some employees just hours after they received dismissal notices.
The cuts, which affect several high-profile agencies under the Department of Health and Human Services, including the FDA, CDC and the National Institutes of Health, are part of a broad plan by President Donald Trump and billionaire ally Elon Musk to shrink the federal government and slash spending.
Health Secretary Robert F. Kennedy Jr. has described the cuts as essential to streamlining a bloated bureaucracy.
However they have included the ouster of top scientists overseeing public health, cancer research and vaccine and drug approvals, raising concerns about how the U.S. will respond to health emergencies, such as the ongoing measles outbreak and spreading bird flu.
Departures at the Food and Drug Administration, considered the world's top drugs regulator, included Peter Stein, the director of the Office of New Drugs in its Center for Drug Evaluation and Research division. He resigned on Tuesday when faced with being fired, according to one source familiar with the matter.
Brian King, the head of the FDA's Center for Tobacco Products division, was fired, according to an email sent by King to FDA staff seen by Reuters. That followed the ouster of Peter Marks, the FDA's highly regarded top vaccine official.
Staff have also been leaving and some employees reviewing products say they are struggling to meet their deadlines.
"The FDA as we've known it is finished, with most of the leaders with institutional knowledge and a deep understanding of product development and safety no longer employed," former Commissioner Robert Califf wrote in a LinkedIn post.
"I believe that history will see this a huge mistake," he wrote. "It will be interesting to hear from the new leadership how they plan to put 'Humpty Dumpty' back together again."
TURNED AWAY AT DOORS
An FDA employee said staff had to present their badges at the building entrance and those who had been fired were given a ticket and told to return home, according to one source. People waited in line for hours not knowing what would happen when they reached the front.
The ticket, seen by Reuters, listed phone numbers for 10 different departments for employees to call to retrieve their "essential" equipment.
An FDA staff member said 17 employees in the press office were let go. FDA's Chief Information Officer Vid Desai said he was also let go.
Fired staff received emails that said their terminations did not reflect on their service, performance or conduct, according to an email seen by Reuters.
Cuts at the FDA's Center for Tobacco Products included the Office of Management and Office of Regulations in their entirety, said the center's former director, Mitch Zeller, citing a contact still at the center.
"I think that this makes it virtually impossible for CTP to regulate tobacco products," Zeller said.
LONG LINES
A line of cars clogged the two main roads leading into the National Institutes of Health's main campus in Bethesda, Maryland, where employees had been notified early Tuesday morning that they were laid off, according to a source.
At the Centers for Disease Control and Prevention, staff who were fired had worked at the National Center for Environmental Health, Substance Abuse and Mental Health Services Administration, and the National Center for Immunization and Respiratory Diseases, including at least one person working on the federal response to measles outbreaks, according to another source.
"What I think is clear and that people should understand is that HHS touches the lives of just about every American and a reorganization and downsizing of this size would typically take months on months of work," said Kevin Griffis, who resigned on March 21 as CDC Director of Communications.
A health official said employees who worked directly for HHS also were fired. HHS officials were not immediately available for comment.
The line to get into the Rockville, Maryland HHS building that houses the Health Resources and Services Administration, the Substance Abuse and Mental Health Services Administration, the Agency for Healthcare Research and Quality, and the Indian Health Service stretched all the way to the parking lot, two sources told Reuters, with only two security guards on site screening everyone attempting to enter.
(Additional reporting by Dan Levine in San Francisco; Chad Terhune in Los Angeles; Julie Steenhuysen in Chicago; Rachael Levy, Ted Hesson and Ahmed Aboulenein in Washington; Patrick Wingrove, Michael Erman and Nathan Layne in New York; and Emma Rumney in London; Editing by Caroline Humer, Frances Kerry, Deepa Babington and Bill Berkrot)
The article discusses mass layoffs at US health agencies initiated by the Trump administration.
The layoffs affect 10,000 staffers at the FDA, CDC, and NIH.
The layoffs are part of a plan to shrink the federal government and reduce spending.
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