Pfizer and Merck collaboration on cancer drug development - Global Banking & Finance Review
The image depicts the logos of Pfizer and Merck, symbolizing their collaboration on innovative cancer medicines. This partnership aims to develop new immuno-oncology drugs to combat various types of cancer, enhancing investment opportunities in the healthcare sector.
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US, GERMAN DRUGMAKERS TEAM UP ON CANCER MEDICINES

Published by Gbaf News

Posted on November 18, 2014

1 min read
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The Associated Press

Pfizer and Merck Announce New Partnership

NEW YORK (AP) — Pfizer says it will partner with German drug and chemical maker Merck in developing potential cancer drugs in a hot new medication class that harnesses the body’s immune system to fight cancer.

Details of the Financial Agreement

Under their agreement, New York-based Pfizer will pay Merck KGaA $850 million initially and up to $2 billion total, based on how many drugs are approved and future revenue.

Impact on Pfizer’s Earnings Forecast

Pfizer says the $850 million payment will cut profit this year, so it’s lowered its 2014 earnings forecast range by a dime, to $1.40 to $1.49 per share.

Development Plans for Innovative Cancer Therapies

The two companies plan to develop drugs to fight multiple cancer types, either alone or in combination with their other cancer treatments. They say they expect next year to start up to 20 patient testing programs of such immuno-oncology drugs.

Key Takeaways

  • Pfizer and Germany’s Merck KGaA formed a strategic alliance in November 2014 to develop and commercialize immuno‑oncology drugs.
  • Pfizer paid an $850 million upfront fee and could pay up to $2 billion in milestones to Merck KGaA.
  • The deal prompted Pfizer to lower its 2014 earnings per share guidance from $1.50–$1.59 to $1.40–$1.49.
  • The collaboration includes up to 20 immuno‑oncology development programs and plans to begin pivotal trials the following year.

References

Frequently Asked Questions

What is the partnership between Pfizer and Merck KGaA?
They formed a global strategic alliance in November 2014 to co‑develop and co‑commercialize immuno‑oncology drugs, notably the anti‑PD‑L1 antibody avelumab.
How much is Pfizer paying Merck KGaA?
Pfizer paid an $850 million upfront fee and may pay up to $2 billion in total based on milestones.
How did the deal affect Pfizer’s financial outlook?
Pfizer lowered its projected 2014 diluted earnings per share from $1.50–$1.59 to $1.40–$1.49 due to the upfront payment.
What clinical development is planned under the alliance?
The companies intend to launch up to 20 immuno‑oncology clinical programs, including up to six potentially pivotal trials starting in 2015.

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