Protein A Resins Market Will Register Sales Growth by 8.1% CAGR, Driven by Surging Focus on Monoclonal Antibody Researches


The Protein A Resins Market is set to grow at an 8.1% CAGR, driven by increasing monoclonal antibody research and biopharmaceutical demand.
According to a recent study by Future Market Insights (FMI), the global protein A resins market is expected to witness high growth during the forecast period. The market is expected to grow from US$ 536.6 Mn in 2020 to over US$ 1.2 Bn by 2031. This reflects a cumulative CAGR of around 8.1% over the forecast period (2021-2031). Increasing researches conducted on monoclonal antibodies are driving demand for protein A resin. Since the commercialization of the first therapeutic monoclonal antibody in 1986, till May 2021, around 100 monoclonal antibody products have been approved by the U.S. FDA and European Medical Agency for the treatment of various diseases such as cancer.
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Monoclonal antibody therapy for the treatment of mild to moderate COVID-19 in patients has also been approved by the FDA under Emergency Use Authorization (EUA).
Studies on monoclonal antibodies have indicated that more monoclonal antibody therapies are in the process of getting FDA approval and can be marketed in the near future to cater to rising demand in the global life sciences industry. Thus, increasing research on monoclonal antibodies (mAb) is expected to fuel the demand and utilization of protein A resin for purification and precipitation purposes.
For the purification of monoclonal antibodies (mAb), different technologies are available which includes membrane chromatography, mixed chromatography, and aqueous two-phase extractions (ATPS). However, protein A resin holds the top position for the purification of mAbs.
With many industries facing issues of leaching of ligand and resistance during the commercialization of monoclonal antibodies (mAbs), the availability of next-generation protein A resins with improved purification conditions, such as alkaline-stability, and with very low ligand leaching, is expected to increase the production and throughput demand for protein therapeutic processes.
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Furthermore, in June 2018, Purolite Life Sciences launched a novel next-generation Protein A agarose resin, Praesto Jetted A50. GE Healthcare, in 2017, introduced a next-generation protein A resin, MabSelect PrismaA, which was designed to enable biopharma manufacturers to improve their mAb purification capacity by up to 40% over GE Healthcare’s existing protein A affinity medium. These product launches are expected give tailwinds to growth registered in the market.
Such developments not only strengthen the company’s existing portfolio but also help to increase their presence at the regional as well as global level.
Key Takeaways from Protein A Resin Study
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“Increasing demand of protein A Resins for biologics production including monoclonal antibody and biosimilars is expected to drive the demand of protein a resin over the decade. To capitalize on existing opportunities, market players are expected to push investment towards product launches and research initiatives,” says the FMI Analyst
Who is Winning?
Some of the leading manufacturers of protein A resin market are focusing on product launch collaboration and partnership strategies for global expansion objectives, thereby, enhancing their market presence.
The key market players covered by FMI include GE Healthcare, Thermo Fisher Scientific, Kaneka Corporation, JNC Corporation, Purolite Life Sciences, Bio-Rad Laboratories, Inc., JSR Corporation (JSR Life Sciences LLC), Repligen, Tosoh Bioscience, Merck Group (Merck Millipore), Novasep Holdings SAS, Agilent Technologies, Inc., GenScript, Abcam PLC (Expedeon Ltd.), Avantor Inc., Takara Bio, PerkinElmer, Inc., Suzhou Nanomicro Technology Co., Ltd.
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The article discusses the growth of the Protein A Resins Market, driven by monoclonal antibody research and biopharmaceutical manufacturing.
Increasing research and development in monoclonal antibodies and biopharmaceutical manufacturing drive the demand for protein A resins.
North America holds the largest market share, with the U.S. as a leading market.
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