Peptide Therapeutics Market Set for Linear Growth at 11% CAGR through 2030; Market to Witness Decline in Near Term Due to COVID-19 Pandemic
According to the report, peptide therapeutics are gaining traction in the pharmaceutical industry, owing to their cost-effectiveness and efficacy in managing numerous disease indications.
Economic factors, such as government policies for start-up companies in emerging economies, increasing FDI, and increasing healthcare expenditure are also driving the use of peptides in therapeutics. Increasing prevalence of cardiovascular and metabolic disorders is expected to provide an impetus to R&D activities in using peptides as therapeutics.
Peptides are the combination of two or more amino acid monomers linked by amide bonds. Researchers has demonstrated that peptide are distinguished from proteins on the basis of size. As a benchmark, molecules with less than 50 amino acids are considered as peptides. Peptides act by binding to specific cell surface receptors and mimics like receptor ligands and help in treatment of diseases by acting on the cell membrane
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Emergence of prominent pharmaceutical and biotech companies, high specificity of peptides leading, advanced and strong pipelines, and patent expiries are the other key factors driving the global peptide therapeutics market, according to FMI’s report.
“Revival of interest in peptides as potential drug candidates because of their low oral bioavailability has been a major factor fuelling growth of the global peptide therapeutics market. Lack of oral efficacy in peptide drug delivery has actually helped researchers to find innovative methods of peptide drug delivery. However, there is still low acceptance among end users; hence, creating awareness could open up opportunities in the market”, said FMI Analyst.
Peptide therapeutics are used for treating prostrate, breast, ovarian and pancreatic cancers. Peptides that are antagonists or agonists of specific receptors in oncology are increasingly being tested at the preclinical stages for their efficacy in cancer treatment. These increasing number of oncology studies indicate that there is an enormous cancer patient pool available globally, which is creating a larger niche for cancer application types in the global peptide therapeutic market.
Parenteral Segment Hold a Major Share of Global Peptide Therapeutics Market
- In terms of route of administration, the global peptide therapeutics market has been classified into parenteral, oral and others.
- The parenteral segment dominated the peptide therapeutics market. The parenteral route of administration is the most common as it ensures faster and better bioavailability, faster onset time and better treatment outcomes. However, with advances in drug delivery technologies there has been a change in the trend of route of administration of therapeutic peptides.
Increasing commercialisation costs and low oral bioavailability of peptide drugs can impede the demand for peptides during the forecast market.
On the basis of disease indication, the global peptide therapeutics market is segmented into cancer, cardiovascular, central nervous systems, metabolic disorders, infection, hematological disorders, gastrointestinal disorders, dermatology, respiratory disorders, and endocrinology. The cancer segment accounts for the highest market share currently and is expected to remain the leading segment in terms of value during the forecast period.
In terms of route of administration, parenteral route of administration is expected to hold more than half the global market share, while the oral route of administration is projected to expand at the highest CAGR in terms of value.
By drug type, generic drugs are expected to register an exceptional CAGR during the forecast period, owing to patent expiries of large number of branded drugs.
Region-wise, North America is the largest market, and will remain so during the forecast period as well. Markets in the Americas and Europe collectively accounted for over 75% revenue share of the global peptide therapeutics market in 2015.
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The market in MEA region is projected to exhibit above average CAGR, owing to increase in prevalence of metabolic disorders and increasing number of pharmaceuticals companies in the region.
The global peptide therapeutics market is fragmented in terms of number of players. Key players in the global peptide therapeutics market include Amgen, Inc., Bachem Holding AG, Eli Lilly and Company, F. Hoffmann-La Roche Ltd., GlaxoSmithKline plc, Novartis AG, Pfizer, Inc., Sanofi, Takeda Pharmaceutical Company Limited and Teva Pharmaceutical Industries Ltd.