
Cholestasis Treatment Market (Forecast Period 2021-2028): The report provides a valuable source of insightful data for business strategists and competitive analysis of Cholestasis Treatment Market. The study covers important knowledge that makes the analysis document a handy resource for managers, analysts, business consultants and different key individuals get ready-to-access and self-analyzed study in conjunction with graphs and tables to assist perceive market trends, drivers and market challenges.It also highlights the restraints and opportunities expected to influence the market’s growth during the said period. The study provides a holistic perspective on the market’s growth throughout the above mentioned forecast period in terms of revenue(in US$ Mn) and Volume (Thousand Units), across different geographies.
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Major Players In This Market Are: Eli Lily and Company, Palmetto Health, Asklepion Pharmaceuticals, LLC, and Abbott Laboratories.
Global Cholestasis Treatment Market – Insights
Cholestasis is a state in which the flow of bile from the liver stops or slows. The condition is divided into two basic types: obstructive and metabolic. The duct system that carries the bile from the liver is blocked in obstructive type of cholestasis. The condition may occur due to gallstone or malignancy. The metabolic type is characterized by issues in the formation of bile in the liver. Genetic factors or side effects of some drugs may lead to metabolic cholestasis. Itchiness, jaundice, pale stool, and dark urine are some of the symptoms of cholestasis.
Obstetric cholestasis is one of the major types of cholestasis. According to the Royal College of Obstetricians and Gynecologists, obstetric cholestasis affects 0.7% of pregnancies in the multiethnic populations in addition to 1.2–1.5% of pregnant women of Indian or Pakistani origin, in England. Genetic and environmental factors impact the epidemiology of obstetric cholestasis. For instance, 2.4% of all pregnancies are affected in Chile.
Cholestasis may have adverse impact on lipid metabolism. Disturbance of the bile from the liver to the gut can lead to accumulation of toxic bile constituents in hepatocytes. This in turn my affect synthetic functionality and lead to low production of enzymes concerned in the lipoprotein metabolism. Decreasing HDL levels and rise of abnormal lipoprotein X in the plasma can disturb lipoprotein discharge at some stage in cholestasis. Therefore, association of cholestasis with several diseases is expected to promote development of efficient diagnostic tests, which is expected to boost growth of the global cholestasis treatment market.
Global Cholestasis Treatment Market Taxonomy
On the basis of drug class, the global cholestasis treatment market is classified into:
◦ Bile Acids
◦ Corticosteroids
◦ Vitamin Supplementation
Global Cholestasis Treatment Market: Drivers
High incidence of obstetric cholestasis is expected to boost growth of the global cholestasis treatment market. For instance, according to a report published in National Center for Biotechnology Information (NCBI), intrahepatic cholestasis of pregnancy (ICP) or obstetric cholestasis is the major liver disease during pregnancy. This reversible disease occurs in the second to third trimester with symptoms such as pruritus (severe itching of the skin) mainly in the palms and soles, serum aminotransferases, and high serum bile acid levels. Therefore, increasing number of pregnancies is also expected to boost growth of the market.
Cholestasis is hereditary condition, which has led to a substantial prevalence of the condition in children. According to NCBI, hereditary disorders of biliary atresia and intrahepatic cholestasis are the major causes of chronic liver disease amongst children. Such scenario is also expected to contribute to growth of the market during the forecast period. Increasing R&D related to cholestasis is also expected to boost the market growth. For instance, a study presented by the Icahn School of Medicine at Mount Sinai, New York at Digestive Disease Week 2019 in San Diego identified a link between intrahepatic cholestasis of pregnancy and nonalcoholic fatty liver disease.
Global Cholestasis Treatment Market: Restraints
However, failure of therapies in the treatment of cholestasis is expected to hamper growth of the global cholestasis treatment market. For instance, in August 2019, a study by King’s College London published in The Lancet found that treatment with ursodeoxycholic acid does not reduce adverse perinatal outcomes in women suffering from intrahepatic cholestasis of pregnancy.
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In this study, the years considered to estimate the market size of Cholestasis Treatment are as follows:
History Year: 2017-2020
Base Year: 2020
Estimated Year: 2021
Forecast Year 2021 to 2028
The next part also sheds light on the gap between supply and consumption. Apart from the mentioned information, growth rate of Cholestasis Treatment Market in 2028 is also explained. Additionally, type wise and application wise consumption tables and figures of Cholestasis Treatment Market are also given.
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