Published by Coherent Market Insights
Posted on September 21, 2021
4 min readLast updated: February 4, 2026
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The Bone Graft Substitutes Market, valued at $1.78B in 2020, is projected to grow at a 4.3% CAGR by 2027, driven by increased spinal fusion surgeries.
Global Bone Graft Substitutes Market
Bone graft substitutes are materials used for the replacement of the missing bones or gum tissues in the body. These are used for filling the null areas of certain body parts, such as the knee, wrist, ribs, etc. The substitutes may be manmade or derived from a donor’s body. The common types of bone graft substitutes are allograft, xenograft, alloplast, and autograft. Allografts are tissues of the donors given to the recipients, but are often not the same as used in knees, hips, or long bones. Bone grafts are the synthetic type of a naturally-occurring substance. A wide variety of bone graft substitutes are available for use in spinal fusion surgery, which is categorized into three main areas, namely, Demineralized Bone Matrix (DBM), Bone Morphogenetic Proteins (BMP), and synthetic bone graft extenders.
The bone graft substitute is osteoinductive, biocompatible, and bioresorbable, and its structure is similar to actual bones. These are cost-effective and easy to use. Bone graft substitutes are extensively used in dental implants, fibular shafts, and others. The sources of bone grafts are Osteoconduction, Osteogenesis, Osteopromotion, and Osteoinduction. These are the biological mechanisms that provide a basis for bone grafting. The spinal fusion surgery is the most common surgery in this were it is used to correct hitches with the small bones of the vertebrae. Spinal fusion removes the motion between vertebrae and helps prevent the stretching of nerves, ligaments, and muscles.
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Global Bone Graft Substitutes Market Segmentation
By application
By product type
By region
Increase in spinal fusion and osteoporosis procedures around the globe is a leading factor for the global bone graft substitutes market growth
Growing population and growing prevalence of bone and joint disorders are the pivotal factors boosting the global bone graft substitutes market development. According to the National Osteoporosis Foundation (NOF), the number of osteoporosis cases is expected to exceed 61 million by 2020. The National Spinal Cord Injury Center, U.S., reported that nearly 12500 new spinal cord injury (SCI) cases emerge each year. Moreover, the International Osteoporosis Foundation (IOF) estimated that around 50% of all osteoporotic hip fractures would be arising in Asia by the year 2050.
In India, the IOF estimated the number of osteoporosis patients to be approximately 26 million. Whereas, in Japan, the total number of hip fractures is estimated to be approximately 238,000 by 2030.
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Key Players of the Global Bone Graft Substitutes Market
The well-known companies operating in the global bone graft substitutes market include Geistlich North America Inc., Medtronic BioHorizons IPH, ACE Surgical Supply Company, Stryker Corporation, RTI Surgical, Inc. LifeNet Health, Institut Straumann AG, Acesurgica Supply Co. Inc., and DePuySynthes.
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The post Bone Graft Substitutes Market Valued at USD 1.78 Billion in 2020 and it is expected to expand At CAGR OF 4.3% by 2021-2027 appeared first on Gatorledger.
The article discusses the growth and trends in the global Bone Graft Substitutes Market from 2020 to 2027.
The increase in spinal fusion surgeries and the prevalence of bone and joint disorders are key drivers.
Major companies include Medtronic, Stryker Corporation, and Geistlich North America Inc.
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