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    Home > Headlines > J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal
    Headlines

    J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal

    Published by Global Banking and Finance Review

    Posted on January 14, 2025

    3 min read

    Last updated: January 27, 2026

    This image features the Johnson & Johnson logo alongside visuals representing neurological drugs, highlighting the company's strategic $14.6 billion acquisition of Intra-Cellular Therapies to enhance its pharmaceuticals division.
    Johnson & Johnson logo with a background of neurological drug imagery - Global Banking & Finance Review
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    Quick Summary

    J&J acquires Intra-Cellular Therapies for $14.6B, enhancing its neurological drug portfolio. The acquisition includes Caplyta, a key treatment for schizophrenia and bipolar disorder.

    J&J Acquires Intra-Cellular for $14.6B to Boost Neurological Drugs

    By Bhanvi Satija and Puyaan Singh

    (Reuters) - Johnson & Johnson said on Monday it would buy neurological drug maker Intra-Cellular Therapies for $14.6 billion, its biggest deal in more than two years, boosting its presence in the market for brain disease treatments.

    The deal would help accelerate growth in J&J's drugs business after the company spun off its consumer health unit in 2023. It has made several transactions in the past few years to boost its pharmaceuticals and medical devices units, including a $13.1 billion deal for Shockwave Medical in 2024.

    "These deals do not happen every day, and as a matter of fact, for us, larger deals are more outliers," said J&J CEO Joaquin Duato, speaking at a major industry conference that kicked off Monday in San Francisco.

    Bankers expect more dealmaking at the conference and in general in 2025, betting activity could exceed $10 billion on expectations for less antitrust scrutiny once President-elect Donald Trump takes office on Jan. 20.

    J&J has offered to buy each share of Intra-Cellular for $132, representing a 39% premium to the stock's closing price on Friday. Shares of Intra-Cellular rose 34% to $128 in afternoon trading, while J&J rose 1.5%.

    The deal would allow J&J to gain access to Intra-Cellular's oral therapy, Caplyta, which is approved in the U.S. to treat schizophrenia and depressive episodes associated with bipolar disorder, and other experimental drugs under development.

    Caplyta brought in $481.3 million in sales in the first nine months of 2024 and some analysts do not expect it to face generic competition until 2040. Analysts expect the treatment to bring in more than $1 billion in sales next year, according to data compiled by LSEG.

    RBC Capital analyst Shagun Singh said the deal fit strategically into J&J's neurological drugs division, an important area for the company.

    But at least one investor raised concerns that it could potentially face a tougher antitrust review.

    "I do have a lot of antitrust concerns about this deal," said Jeff Jonas, portfolio manager at Gabelli Funds, which owns about 193,035 shares of J&J.

    Jonas said there was an overlap in the products of the two companies, given J&J has a late-stage depression drug and a schizophrenia treatment already on the market.

    J&J's expectation that it would close the deal "later this year" seems to incorporate a tough review even under the new administration, he said.

    The healthcare giant's schizophrenia drug paliperidone, sold under multiple brand names such as Invega and Xeplion, brought in $3.16 billion in sales in the first nine months of 2024.

    J&J said it expects to fund the latest transaction through a combination of cash on hand and debt. Duato said the majority of J&J's deal activity was through smaller acquisitions, having completed about 75 in 2024 alone.

    (Reporting by Puyaan Singh and Bhanvi Satija in Bengaluru; Editing by Shilpi Majumdar)

    Key Takeaways

    • •Johnson & Johnson to acquire Intra-Cellular Therapies for $14.6 billion.
    • •The deal enhances J&J's presence in the brain disease treatment market.
    • •Intra-Cellular's Caplyta is a key asset in the acquisition.
    • •Analysts predict Caplyta sales to exceed $1 billion next year.
    • •Potential antitrust concerns due to product overlap.

    Frequently Asked Questions about J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal

    1What is the main topic?

    The main topic is Johnson & Johnson's acquisition of Intra-Cellular Therapies for $14.6 billion to expand its neurological drug offerings.

    2Why is this deal significant?

    This is J&J's largest deal in over two years, significantly boosting its presence in the brain disease treatment market.

    3What are potential concerns about the deal?

    There are potential antitrust concerns due to product overlap between J&J and Intra-Cellular.

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