Tekla Life Sciences Investors Paid Distribution

On September 28, 2018, Tekla Life Sciences Investors paid a distribution of $0.40 per share. It is currently estimated that this distribution is derived from net realized short-term capital gains and return of capital or other capital source. The composition of this and subsequent distributions may vary from quarter to quarter because it may be materially impacted by future realized gains and losses on securities. The aggregate of the net unrealized appreciation of portfolio securities and net realized gains on sale of securities is $161,473,641, of which $131,926,759 represents net unrealized appreciation of portfolio securities.

The following table sets forth the estimated amounts of the current distribution, paid on September 28, 2018, and the cumulative distributions paid this fiscal year-to-date from the following sources: net investment income, net realized short-term capital gains, net realized long-term capital gains, return of capital or other capital source. The Fund estimates that it has distributed more than its income and net realized capital gains; therefore, a portion of your distribution may be a return of capital. A return of capital may occur, for example, when some or all of the money that you have invested in the Fund is paid back to you. A return of capital distribution does not necessarily reflect the Funds investment performance and should not be confused with ˜yield or ˜income. All amounts are expressed per common share.

Current Distribution

Percentage Breakdown of Current Distribution

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Total Cumulative Distributions for the Fiscal Year to Date1

Percentage Breakdown of the Total Cumulative Distributions for the Fiscal Year to Date1

Net Investment Income$0.00000%$0.00000%
Net Realized ST Cap Gains$0.313478%$0.824451%
Net Realized LT Cap Gains$0.00000%$0.245515%

Return of Capital or Other Capital Source

$0.0866

22%

$0.5601

34%

TOTAL (per common share):$0.4000100%$1.6300100%

The table below includes information relating to the Funds performance based on its NAV for certain periods.

Average annual return at NAV for the period from July 31, 2013 through July 31, 201810.28%
Annualized current distribution rate expressed as percentage of NAV as of July 31, 20187.79%

Cumulative total return at NAV for the fiscal year, through July 31, 20182

1.23%

Cumulative fiscal year-to-date distribution rate expressed as a percentage of NAV as of July 31, 20181

7.94%

You should not draw any conclusions about the Funds investment performance from the amount of this distribution or from the terms of the Funds managed distribution policy.

The amounts and sources of distributions reported in this press release are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Funds investment experience during the remainder of its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Tekla Life Sciences Investors (NYSE: HQL) is a closed-end fund that invests in companies in the healthcare industry.

Tekla Capital Management LLC, the Funds investment adviser, is a Boston, MA based healthcare-focused investment manager with approximately $3.0 billion of net assets under management as of June 30, 2018. Tekla also serves as investment adviser to Tekla Healthcare Investors (NYSE: HQH), Tekla Healthcare Opportunities Fund (NYSE: THQ) and Tekla World Healthcare Fund (NYSE: THW), closed-end funds that invest in companies in the healthcare and life sciences industries. Information regarding the Funds and Tekla Capital Management LLC can be found at www.teklacap.com.

Destra Capital Investments is the Funds marketing and investor support services agent. Please contact Destra Capital Investments at [email protected] or call (877) 855-3434 if you have any questions regarding HQL.

1 The Funds current fiscal year began on October 1, 2017. 2 Cumulative total return at NAV is the percentage change in the Funds NAV and includes all distributions and assumes the reinvestment of those distributions for the period of September 30, 2017 through July 31, 2018.

Destra Capital Investments
877-855-3434
[email protected]

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