On Friday, November 16, Immunomic Therapeutics Inc. (ITI) Scientist Amit Adhikara will present at the Society for NeuroOncology 2018 Annual Meeting in New Orleans. The presentation will focus on Immunomics recently-expanded investigational UNiversal Intracellular Targeted Expression (UNITE„¢) platform and its application in immuno-oncology, specifically glioblastoma multiforme (GBM).
Immunomics technology platform has the potential to utilize the bodys natural biochemistry to develop a broad immune response, including antibody production, cytokine release and critical immunological memory. This approach could put Immunomics platform technology at the crossroads of immunotherapies in a number of illnesses, including cancer, allergy and infectious diseases. UNITE is currently being employed in a Phase II clinical trial as a cancer immunotherapy.
Details of Immunomics poster presentation are below:
Who: Amit Adhikara, Scientist at Immunomic Therapeutics
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What: Development of Cytomegalovirus (CMV) Based DNA Vaccines for GBM Using the UNITE Platform
When: Friday, November 16 at 7:30 p.m. CST
Where: Marriott Hotel, 555 Canal Street, New Orleans, LA, 70130
ITIs investigational UNITE platform, or UNiversal Intracellular Targeted Expression, is thought to work by encoding the Lysosomal Associated Membrane Protein, an endogenous protein in humans. In this way, ITIs vaccines (DNA or RNA) have the potential to utilize the bodys natural biochemistry to develop a broad immune response including antibody production, cytokine release and critical immunological memory. This approach could put UNITE technology at the crossroads of immunotherapies in a number of illnesses, including cancer, allergy and infectious diseases. UNITE is currently being employed in Phase II clinical trials as a cancer immunotherapy. ITI is also collaborating with academic centers and biotechnology companies to study the use of UNITE in cancer types of high mortality, including cases where there are limited treatment options like glioblastoma and acute myeloid leukemia. ITI believes that these early clinical studies may provide a proof of concept for UNITE therapy in cancer, and if successful, set the stage for future studies, including combinations in these tumor types and others. Preclinical data is currently being developed to explore whether LAMP nucleic acid constructs may amplify and activate the immune response in highly immunogenic tumor types and be used to create immune responses to tumor types that otherwise do not provoke an immune response.
About Immunomic Therapeutics, Inc.
Immunomic Therapeutics, Inc. (ITI) is a privately-held, clinical stage biotechnology company pioneering the development of vaccines through its proprietary technology platform, UNiversal Intracellular Targeted Expression (UNITE„¢), which is designed to utilize the bodys natural biochemistry to generate broad immune responses. ITIs UNITE platform has broad therapeutic applications in oncology, including viral antigens, cancer antigens, neoantigens and antigen-derived antibodies as biologics and ITI has built a large pipeline from UNITE with six oncology programs and two allergy programs. ITI’s technology has been deployed in over 135 oncology patients and 210 allergy patients and in oncology, has demonstrated survival benefit and immune system activation in the clinic. Due to its expertise in the field, ITI entered into a significant allergy partnership with Astellas Pharma and has formed several academic collaborations with leading Immuno-oncology researchers at Fred Hutchinson Cancer Research Institute, Johns Hopkins University of Medicine, and Duke University. ITI maintains its headquarters in Rockville, Maryland. For more information, please visit www.immunomix.com.
Immunomic Therapeutics, Inc.
Sia Anagnostou, 717-327-1822